Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.13.8 extracted from

  • Ryu, S.D.; Yi, H.G.; Cha, Y.N.; Kang, J.H.; Kang, J.S.; Jeon, Y.C.; Park, H.K.; Yu, T.M.; Lee, J.N.; Park, C.S.
    Flavin-containing monooxygenase activity can be inhibited by nitric oxide-mediated S-nitrosylation (2004), Life Sci., 75, 2559-2572.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
NO overproduced NO in liver causes the suppression of FMO3 activity directly via reversible S-nitrosylation. Overproduced NO may be responsible, at least in part, for the impairment of the detoxification or metabolism by FMOs of xenobiotics, which include a number of therapeutic drugs Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver FMO3 is the major FMO Homo sapiens
-

Synonyms

Synonyms Comment Organism
FMO3
-
Homo sapiens