Cloned (Comment) | Organism |
---|---|
gene FMO3, DNA and amino acid sequence determination and analysis, transient expression in Hep-G2 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | the HepG2 model is suitable for the study of FMO3 regulation, deletion analysis of FMO3/luciferase reporter constructs, domains A-I, and specific transcription factor responsive elements identified by DNA-protein binding reactions and site-directed mutagenesis of FMO3 reporter constructs, functional analysis of the FMO3 HNF3, and C/EBP elements, FMO3 promoter analysis, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | human FMO3 regulatory elements, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P31513 | FMO3; gene FMO3 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
additional information | no expression of FMO3 in Hep-G2 cells, decreased hepatic nuclear factor HNF4alpha levels and DNA hypermethylation are the mechanisms suppressing Hep-G2 FMO3 expression | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | human FMO3 regulatory elements, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
flavin containing monooxygenase 3 | - |
Homo sapiens |
FMO3 | - |
Homo sapiens |