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Literature summary for 1.14.13.82 extracted from
- Molecular cloning of Streptomyces genes encoding vanillate demethylase (2006), Biosci. Biotechnol. Biochem., 70, 2316-2319.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| genes vanA and vanB, DNA and amino acid sequence determination and analysis, genetic organization, sequence comparison, functional coexpression of genes vanA and vanB in Streptomyces lividans strain 1326 from the high-copy plasmid pIJ702, selection on veratric acid | Streptomyces sp. |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | binding sequence motif of iron-sulfur cluster, overview | Streptomyces sp. |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Streptomyces sp. | the enzyme forms a vanillate demethylase complex of VanA, a terminal oxygenase subunit, with VanB, a ferredoxin-like subunit, performing demethylation of vanillic acid and veratric acid | ? | - |
? | |
| vanillic acid + NADH + H+ + O2 | Streptomyces sp. | - |
protocatechuic acid + NAD+ + H2O + formaldehyde | procatechuic acid is 3,4-dihydroxybenzoate | ? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces sp. | - |
genes vanA and vanB | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme forms a vanillate demethylase complex of VanA, a terminal oxygenase subunit, with VanB, a ferredoxin-like subunit, performing demethylation of vanillic acid and veratric acid | Streptomyces sp. | ? | - |
? | |
| vanillic acid + NADH + H+ + O2 | - |
Streptomyces sp. | protocatechuic acid + NAD+ + H2O + formaldehyde | procatechuic acid is 3,4-dihydroxybenzoate | ? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| vanAB | - |
Streptomyces sp. |
| vanillate demethylase | - |
Streptomyces sp. |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | binding sequence motif, overview | Streptomyces sp. | |
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