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Literature summary for 1.14.14.1 extracted from

  • Syed, K.; Porollo, A.; Lam, Y.W.; Grimmett, P.E.; Yadav, J.S.
    CYP63A2, a catalytically versatile fungal P450 monooxygenase capable of oxidizing higher-molecular-weight polycyclic aromatic hydrocarbons, alkylphenols, and alkanes (2013), Appl. Environ. Microbiol., 79, 2692-2702.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pichia pastoris Phanerodontia chrysosporium

Organism

Organism UniProt Comment Textmining
Phanerodontia chrysosporium
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzo(a)pyrene + [reduced NADPH-hemoprotein reductase] + O2
-
Phanerodontia chrysosporium ?
-
?
benzo(ghi)perylene + [reduced NADPH-hemoprotein reductase] + O2
-
Phanerodontia chrysosporium ?
-
?
fluoranthene + [reduced NADPH-hemoprotein reductase] + O2
-
Phanerodontia chrysosporium ?
-
?
additional information no activity with fluorene, anthracene, phenanthrene, and acenaphthene Phanerodontia chrysosporium ?
-
?
additional information the enzyme also acts as an alkane-hydroxylase that oxidizes n-alkanes with various chain lengths (C9to C12and C15to C19), as well as alkyl side chains (C3to C9) in alkylphenols. CYP63A2 shows preferential oxidation of long-chain alkylphenols and alkanes Phanerodontia chrysosporium ?
-
?
pyrene + [reduced NADPH-hemoprotein reductase] + O2
-
Phanerodontia chrysosporium ?
-
?

Synonyms

Synonyms Comment Organism
CYP63A2
-
Phanerodontia chrysosporium
cytochrome P450 monooxygenase
-
Phanerodontia chrysosporium