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Literature summary for 1.14.14.16 extracted from

  • Blom, S.; F๖rlin, L.; Andersson, T.B.
    Characterisation of head kidney and liver microsomal 17-hydroxyprogesterone 21-hydrolase activity in rainbow trout (Oncorhynchus mykiss) and the lack of regulatory effects of ACTH (2001), Fish Physiol. Biochem., 24, 1-8.
No PubMed abstract available
Search for more literature for 1.14.14.16

Inhibitors

Inhibitors Comment Organism Structure
progesterone
-
 Oncorhynchus mykiss

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0038
-
 17-hydroxyprogesterone head kidney microsomes Oncorhynchus mykiss
0.031
-
 17-hydroxyprogesterone liver microsomes Oncorhynchus mykiss

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
17-hydroxyprogesterone + NADPH + O2 Oncorhynchus mykiss
-
 corticosteroids + NADP+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Oncorhynchus mykiss
-
 rainbow trout
-

Source Tissue

Source Tissue Comment Organism Textmining
interrenal cell
-
 Oncorhynchus mykiss
-
liver
-
 Oncorhynchus mykiss
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17-hydroxyprogesterone + NADPH + O2
-
 Oncorhynchus mykiss corticosteroids + NADP+ + H2O
-
 ?
17alpha-hydroxyprogesterone + NADH + O2
-
 Oncorhynchus mykiss 17,21-dihydroxyprogesterone + NAD+ + H2O
-
 ?

pH Range

pH Minimum pH Maximum Comment Organism
7.5 8.5
-
 Oncorhynchus mykiss