Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.17 extracted from

  • Kim, Y.S.; Cho, J.H.; Park, S.; Han, J.Y.; Back, K.; Choi, Y.E.
    Gene regulation patterns in triterpene biosynthetic pathway driven by overexpression of squalene synthase and methyl jasmonate elicitation in Bupleurum falcatum (2011), Planta, 233, 343-355.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
squalene + AH2 + O2 Bupleurum falcatum
-
(S)-squalene-2,3-epoxide + A + H2O
-
?

Organism

Organism UniProt Comment Textmining
Bupleurum falcatum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Bupleurum falcatum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
squalene + AH2 + O2
-
Bupleurum falcatum (S)-squalene-2,3-epoxide + A + H2O
-
?

Synonyms

Synonyms Comment Organism
squalene epoxidase
-
Bupleurum falcatum

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Bupleurum falcatum

Expression

Organism Comment Expression
Bupleurum falcatum overexpression of the squalene synthase 1 gene in the sense orientation increases the mRNA accumulation of downstream genes such as squalene epoxidase. Methyl jasmonate treatment of wild type roots enhances the expression of the enzyme up