Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
squalene + AH2 + O2 | Bupleurum falcatum | - |
(S)-squalene-2,3-epoxide + A + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bupleurum falcatum | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | - |
Bupleurum falcatum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
squalene + AH2 + O2 | - |
Bupleurum falcatum | (S)-squalene-2,3-epoxide + A + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
squalene epoxidase | - |
Bupleurum falcatum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Bupleurum falcatum |
Organism | Comment | Expression |
---|---|---|
Bupleurum falcatum | overexpression of the squalene synthase 1 gene in the sense orientation increases the mRNA accumulation of downstream genes such as squalene epoxidase. Methyl jasmonate treatment of wild type roots enhances the expression of the enzyme | up |