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Literature summary for 1.14.14.18 extracted from
- Multiplicity of heme oxygenase isozymes. HO-1 and HO-2 are different molecular species in rat and rabbit (1989), J. Biol. Chem., 264, 1323-1328.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 30000 | - |
x * 30000, liver heme oxygenase-1, SDS-PAGE | Rattus norvegicus |
| 30700 | - |
x * 30700, liver heme oxygenase-1, SDS-PAGE | Oryctolagus cuniculus |
| 36000 | - |
x * 36000, heme oxygenase-2, SDS-PAGE | Oryctolagus cuniculus |
| 36000 | - |
x * 36000, testis heme oxygenase-2, SDS-PAGE | Rattus norvegicus |
| 42000 | - |
x * 42000, heme oxygenase-2, SDS-PAGE | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
2 isoforms: heme oxygenase-1, inducible, heme oxygenase-2, constitutive | - |
| Rattus norvegicus | - |
2 isoforms: heme oxygenase-1, inducible | - |
| Rattus norvegicus | - |
heme oxygenase-2, constitutive | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Oryctolagus cuniculus | - |
| testis | - |
Rattus norvegicus | - |
| testis | - |
Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0064 | - |
testis heme oxygenase-2, partialy purified | Oryctolagus cuniculus |
| 0.095 | - |
testis heme oxygenase-2 | Rattus norvegicus |
| 0.104 | - |
liver heme oxygenase-1 | Rattus norvegicus |
| 0.138 | - |
liver heme oxygenase-1 | Oryctolagus cuniculus |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 36000, heme oxygenase-2, SDS-PAGE | Oryctolagus cuniculus |
| ? | x * 42000, heme oxygenase-2, SDS-PAGE | Oryctolagus cuniculus |
| ? | x * 30000, liver heme oxygenase-1, SDS-PAGE | Rattus norvegicus |
| ? | x * 36000, testis heme oxygenase-2, SDS-PAGE | Rattus norvegicus |
| ? | x * 30700, liver heme oxygenase-1, SDS-PAGE | Oryctolagus cuniculus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
- |
Rattus norvegicus |
| 50 | - |
10 min, 80% loss of liver heme oxygenase-1 and testis heme oxygenase 2 activity | Oryctolagus cuniculus |
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