Application | Comment | Organism |
---|---|---|
medicine | potential therapeutic target in cancer | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolane | 1 mM, potent inhibitor | Rattus norvegicus | |
Cr-containing protoporphyrin IX | potent inhibitor | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P06762 | - |
- |
Purification (Comment) | Organism |
---|---|
hydroxylapatite column chromatography and POROS-HQ column chromatography | Rattus norvegicus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.712 | - |
HO-2 | Rattus norvegicus |
8.413 | - |
HO-1 | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
heme + electron donor + O2 | - |
Rattus norvegicus | biliverdin + Fe2+ + CO + oxidized eletron donor + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HO-1 | - |
Rattus norvegicus |