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Literature summary for 1.14.14.18 extracted from

  • Li, H.Y.; Zhong, Y.F.; Wu, S.Y.; Shi, N.
    NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells (2007), Chem. Res. Toxicol., 20, 1242-1251.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information heme oxygenase-1 is induced by tert-butylhydroquinone and by deltamethrin via activation of Nrf2, overview Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
semiquantitative RT-PCR expression analysis of HO-1 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
heme + AH2 + O2 Rattus norvegicus the gene encoding HO-1 is a Nrf2-regulated gene. NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells, e.g. by H2O2 and 6-hydroxydopamine biliverdin + Fe2+ + CO + A + H2O
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus P06762
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Source Tissue

Source Tissue Comment Organism Textmining
PC-12 cell a adrenal pheochromocytoma cell line Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heme + AH2 + O2
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Rattus norvegicus biliverdin + Fe2+ + CO + A + H2O
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heme + AH2 + O2 the gene encoding HO-1 is a Nrf2-regulated gene. NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells, e.g. by H2O2 and 6-hydroxydopamine Rattus norvegicus biliverdin + Fe2+ + CO + A + H2O
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?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
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Rattus norvegicus
HO-1
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Rattus norvegicus