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Literature summary for 1.14.14.18 extracted from

  • Kivelae, A.M.; Kansanen, E.; Jyrkkaenen, H.K.; Nurmi, T.; Ylae-Herttuala, S.; Levonen, A.L.
    Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells (2008), J. Nutr., 138, 1263-1268.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information the enzyme expression is induced by enterolactone from enterobacteria through activation of nuclear factor-E2-related factor 2, Nrf2, in endothelial cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme has anti-inflammatory function in the vascular system via production of antioxidants bilirubin and biliverdin as well as CO, the enzyme contributes to cardiovascular health ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09601
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
Homo sapiens
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HUVEC human umbelical vein endothelial cells, expression analysis Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme has anti-inflammatory function in the vascular system via production of antioxidants bilirubin and biliverdin as well as CO, the enzyme contributes to cardiovascular health Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
Homo sapiens
HO-1
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Homo sapiens