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Literature summary for 1.14.14.18 extracted from

  • Dorresteijn, M.J.; Paine, A.; Zilian, E.; Fenten, M.G.; Frenzel, E.; Janciauskiene, S.; Figueiredo, C.; Eiz-Vesper, B.; Blasczyk, R.; Dekker, D.; Pennings, B.; Scharstuhl, A.; Smits, P.; Larmann, J.; Theilmeier, G.; van der Hoeven, J.G.; Wagener, F.A.; Pickkers, P.; Immenschuh, S.
    Cell-type-specific downregulation of heme oxygenase-1 by lipopolysaccharide via Bach1 in primary human mononuclear cells (2015), Free Radic. Biol. Med., 78, 224-232.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
dendritic cell
-
Homo sapiens
-
granulocyte
-
Homo sapiens
-
macrophage
-
Mus musculus
-
macrophage
-
Homo sapiens
-
monocyte
-
Homo sapiens
-
monocytic leukemia cell
-
Homo sapiens
-
peripheral blood mononuclear cell
-
Homo sapiens
-
peripheral blood mononuclear cell CD14+ Homo sapiens
-

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
Mus musculus
heme oxygenase-1
-
Homo sapiens
HO-1
-
Mus musculus
HO-1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens lipopolysaccharide downregulates isoform HO-1 in primary human peripheral blood mononuclear cells, CD14+ monocytes, macrophages, dendritic cells, and granulocytes down
Homo sapiens lipopolysaccharide upregulates isoform HO-1 in human monocytic leukemia cell lines. Bach1 is a critical transcriptional repressor of isoform HO-1 up
Mus musculus lipopolysaccharide upregulates isoform HO-1 in in primary murine macrophages up