Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ketoconazole | - |
Pelophylax lessonae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pregnenolone + AH2 + O2 | Pelophylax lessonae | - |
17alpha-hydroxypregnenolone + A + H2O | - |
? | |
progesterone + AH2 + O2 | Pelophylax lessonae | - |
17alpha-hydroxyprogesterone + A + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pelophylax lessonae | - |
- |
- |
Pelophylax lessonae | - |
male frogs | - |
Purification (Comment) | Organism |
---|---|
native enzyme partially from brain microsomes | Pelophylax lessonae |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | telencephalon, diencephalon, mesencephalon, metencephalon. Immunoreactivity is almost exclusively located in neurons | Pelophylax lessonae | - |
brain | distribution in the telencephalon, diencephalon, mesencephalon and metencephalon, detailed expression analysis, overview | Pelophylax lessonae | - |
diencephalon | - |
Pelophylax lessonae | - |
metencephalon | - |
Pelophylax lessonae | - |
pars distalis | of pituitary | Pelophylax lessonae | - |
pars intermedia | of pituitary | Pelophylax lessonae | - |
pituitary gland | pars distalis, pars intermedia | Pelophylax lessonae | - |
pituitary gland | in the pars distalis and pars intermedia of the pituitary, detailed expression analysis, overview | Pelophylax lessonae | - |
telencephalon | - |
Pelophylax lessonae | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pregnenolone + AH2 + O2 | - |
Pelophylax lessonae | 17alpha-hydroxypregnenolone + A + H2O | - |
? | |
progesterone + AH2 + O2 | - |
Pelophylax lessonae | 17alpha-hydroxyprogesterone + A + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cytochrome P450 17alpha-hydroxylase/C17,20-lyase | - |
Pelophylax lessonae |
P450c17 | - |
Pelophylax lessonae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
24 | - |
assay at | Pelophylax lessonae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Pelophylax lessonae |