Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced adrenodoxin + O2 | Rattus norvegicus | mitochondrial cytochrome P450 forms a complex with the substrate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced adrenodoxin + O2 | - |
Rattus norvegicus | 5beta-cholestane-3alpha,7alpha,12alpha,27-tetrol + oxidized adrenodoxin + H2O | - |
? | |
5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced adrenodoxin + O2 | mitochondrial cytochrome P450 forms a complex with the substrate | Rattus norvegicus | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | mitochondrial cytochrome-P450 forms an enzyme-substrate complex with 5beta-cholestane-3alpha,7alpha,12alpha-triol with Km value very similar to the Km value of 26-hydroxylation | Rattus norvegicus |