Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
calcidiol + NADPH + H+ + O2 | Homo sapiens | - |
secalciferol + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
renal cell carcinoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
calcidiol + NADPH + H+ + O2 | - |
Homo sapiens | secalciferol + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP24A1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the enzyme is upregulated in tumor cells compared with normal tissue | up |
General Information | Comment | Organism |
---|---|---|
physiological function | upregulated gene expression of CYP24A1 leads to a misbalance of vitamin D metabolites in clear cell renal cell carcinomas and thus contributing to its pathogenesis | Homo sapiens |