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Literature summary for 1.14.15.18 extracted from

  • Yoshida, T.; Yoshida, N.; Nakamura, A.; Monkawa, T.; Hayashi, M.; Saruta, T.
    Cloning of porcine 25-hydroxyvitamin D3 1alpha-hydroxylase and its regulation by cAMP in LLC-PK1 cells (1999), J. Am. Soc. Nephrol., 10, 963-970.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
8-bromo-cAMP enhances mRNA expression level Sus scrofa
forskolin enhances mRNA expression level Sus scrofa

Cloned(Commentary)

Cloned (Comment) Organism
expression in LLC-PK1-cells Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Sus scrofa 5739
-

Organism

Organism UniProt Comment Textmining
Sus scrofa Q9XS57
-
-

Reaction

Reaction Comment Organism Reaction ID
calcidiol + 2 reduced adrenodoxin + 2 H+ + O2 = calcitriol + 2 oxidized adrenodoxin + H2O cytochrome P-450 enzyme Sus scrofa
a

Source Tissue

Source Tissue Comment Organism Textmining
kidney proximal tubular cells Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
calcidiol + NADPH + O2 highly specific for calcidiol, calcidiol is identical with 25-hydroxycholecalciferol Sus scrofa calcitriol + NADP+ + H2O calcitriol is identical with 1,25-dihydroxycholecalciferol ?

Synonyms

Synonyms Comment Organism
CYB27B1
-
 Sus scrofa