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Literature summary for 1.14.16.1 extracted from

  • Han, A.Y.; Lee, A.Q.; Abu-Omar, M.M.
    EPR and UV-Vis studies of the nitric oxide adducts of bacterial phenylalanine hydroxylase: effects of cofactor and substrate on the iron environment (2006), Inorg. Chem., 45, 4277-4283.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information thermodynamics of iron nitrosyl formation Chromobacterium violaceum

Metals/Ions

Metals/Ions Comment Organism Structure
Iron non-heme iron, required, effects of cofactor and substrate on the iron environment, the abilities of nitric oxide to behave as an oxygen mimic and a spectroscopic probe of ferrous iron are used to investigate the geometric and electronic effects of cofactor and substrate binding to cPAH by electron paramagnetic resonance (EPR) and UV-Vis spectroscopies, overview Chromobacterium violaceum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-phenylalanine + tetrahydrobiopterin + O2 Chromobacterium violaceum
-
L-tyrosine + 4a-hydroxy-tetrahydrobiopterin
-
?

Organism

Organism UniProt Comment Textmining
Chromobacterium violaceum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-phenylalanine + 6,7-dimethyl-tetrahydrobiopterin + O2
-
Chromobacterium violaceum L-tyrosine + 6,7-dimethyl-4a-hydroxy-tetrahydrobiopterin
-
?
L-phenylalanine + tetrahydrobiopterin + O2
-
Chromobacterium violaceum L-tyrosine + 4a-hydroxy-tetrahydrobiopterin
-
?
additional information EPR and UV-Vis studies of enzyme-nitric oxide adducts, increase in NO affinity in the presence of substrate, overview Chromobacterium violaceum ?
-
?

Synonyms

Synonyms Comment Organism
PAH
-
Chromobacterium violaceum
phenylalanine hydroxylase
-
Chromobacterium violaceum