Any feedback?
Literature summary for 1.14.16.2 extracted from
- Tyrosine hydroxylase positive neurons and their contacts with vasoactive intestinal polypeptide-containing fibers in the hypothalamus of the diurnal murid rodent, Arvicanthis niloticus (2007), J. Chem. Neuroanat., 33, 131-139.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tyrosine + tetrahydrobiopterin + O2 | Rattus norvegicus | - |
3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin + H2O | - |
? |  |
| L-tyrosine + tetrahydrobiopterin + O2 | Arvicanthis niloticus | - |
3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin + H2O | - |
? | |
| additional information | Arvicanthis niloticus | in nocturnal species, rhythms in tyrosine hydroxylase-containing neurons in the hypothalamus appear to be responsible for rhythms in prolactin secretion, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arvicanthis niloticus | - |
the unstriped Nile grass rat, female animals | - |
| Rattus norvegicus | - |
Sprague-Dawley rat, female animals | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| brain | - |
Arvicanthis niloticus | - |
| forebrain | cells in the basal forebrain | Arvicanthis niloticus | - |
| hypothalamus | - |
Rattus norvegicus | - |
| hypothalamus | - |
Arvicanthis niloticus | - |
| additional information | comparison of enzyme expressing cells of the diurnal rodent Arvicanthis niloticus with the enzyme of the nocturnal rodent Rattus norvegicus, no enzyme in cells of the basal forebrain, vasoactive intestinal polypeptide colocalizes with the enzyme, enzyme distribution, overview | Rattus norvegicus | - |
| additional information | comparison of enzyme expressing cells of the diurnal rodent Arvicanthis niloticus with the enzyme of the nocturnal rodent Rattus norvegicus, vasoactive intestinal polypeptide colocalizes with the enzyme, enzyme distribution, overview | Arvicanthis niloticus | - |
| neuron | - |
Rattus norvegicus | - |
| neuron | - |
Arvicanthis niloticus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tyrosine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin + H2O | - |
? | |
| L-tyrosine + tetrahydrobiopterin + O2 | - |
Arvicanthis niloticus | 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin + H2O | - |
? | |
| additional information | in nocturnal species, rhythms in tyrosine hydroxylase-containing neurons in the hypothalamus appear to be responsible for rhythms in prolactin secretion, overview | Arvicanthis niloticus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| tyrosine hydroxylase | - |
Rattus norvegicus |
| tyrosine hydroxylase | - |
Arvicanthis niloticus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| tetrahydrobiopterin | - |
Rattus norvegicus | |
| tetrahydrobiopterin | - |
Arvicanthis niloticus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
