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Literature summary for 1.14.17.1 extracted from

  • Terland, O.; Flatmark, T.
    Anion- and pH-dependent activation of the soluble form of dopamine beta-hydroxylase (2003), Biochem. J., 369, 675-679.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.17.1

Activating Compound

Activating Compound Comment Organism Structure
acetate the enzyme is inactive inactive in absence of activating anion at pH 5.1-5.3, high catalytic activity in presence of 0.2 M acetate buffer Bos taurus
Cl- the enzyme is inactive inactive in absence of activating anion at pH 5.1-5.3, high catalytic activity in presence of 0.05-0.6 M Cl- in 50 mM Mes buffer. 0.6 M Cl- increases the optimum concentration of ferrocyanide from 0.25 mM to 2 mM Bos taurus
phosphate the enzyme is inactive inactive in absence of activating anion at pH 5.1-5.3, high catalytic activity in presence of 0.1 M phosphate buffer Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal medulla
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tyramine + ascorbate + ferrocyanide
-
 Bos taurus octopamine + dehydroascorbate + ?
-
 ?
tyramine + ascorbate + N,N,N',N'-tetramethyl-p-phenylenediamine
-
 Bos taurus octopamine + dehydroascorbate + ?
-
 ?
tyramine + ascorbate + N,N-dimethyl-p-phenylenediamine
-
 Bos taurus octopamine + dehydroascorbate + ?
-
 ?

Synonyms

Synonyms Comment Organism
DBH
-
 Bos taurus
dopamine beta-hydroxylase
-
 Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 without anion activation or reaction with N,N,NĀ‘,NĀ‘-tetramethyl-p-phenylenediamine activated with 0.6 M Cl- Bos taurus