Inhibitors | Comment | Organism | Structure |
---|---|---|---|
broussonin C | competitive inhibition | Agaricus bisporus | |
kazinol C | competitive inhibition | Agaricus bisporus | |
kazinol D | - |
Agaricus bisporus | |
kazinol F | competitive inhibition | Agaricus bisporus | |
kazinol S | competitive inhibition, i.e. 5'-(2-methylbut-3-en-2-yl)-6''-(3-methylbut-2-enyl)-5''-(2,3-epoxy-3-methylbytyl)-2',4',3'',4''-tetrahydroxy diphenylpropane | Agaricus bisporus | |
kazinol T | i.e. 5'-(2-methylbut-3-en-2-yl)-6''-(3-methylbut-2-enyl)-4'',5''-[(2-(1-hydroxy-1-methylethyl)]-dihydrofuranyl)-2',4',3''-trihydroxy diphenylpropane | Agaricus bisporus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.18 | - |
L-tyrosine | in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | |
0.36 | - |
L-Dopa | in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + L-dopa + O2 | - |
Agaricus bisporus | L-dopa + dopaquinone + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
polyphenol oxidase | - |
Agaricus bisporus |
PPO | - |
Agaricus bisporus |
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00043 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | broussonin C | |
0.00057 | - |
using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | broussonin C | |
0.00096 | - |
using L-tyrosine as substrate, using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol F | |
0.0017 | - |
using L-DOPA as substrate, using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol F | |
0.0155 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol C | |
0.0179 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol S | |
0.0228 | - |
using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol C | |
0.0269 | - |
using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol S | |
0.1031 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol T | |
0.1647 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol D | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol D | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kazinol T |