Literature summary for 1.14.19.1 extracted from

Lausada, N.; de Gomez Dumm, I.N.; Raimondi, J.C.; de Alaniz, M.J.
Effect of cyclosporine and sirolimus on fatty acid desaturase activities in cultured HEPG2 cells (2009), Transplant. Proc., 41, 1865-1870.

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Inhibitors

Inhibitors	Comment	Organism	Structure
cyclosporin A	-	Homo sapiens
Rapamycin	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Hep-G2 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
palmitoyl-CoA + NADH + H+ + O2	main substrate	Homo sapiens	palmitoleoyl-CoA + NAD+ + H2O	-	?
stearoyl-CoA + NADH + H+ + O2	main substrate	Homo sapiens	oleoyl-CoA + NAD+ + H2O	-	?

Synonyms

Synonyms	Comment	Organism
DELTA9 desaturase	-	Homo sapiens
fatty acid desaturase	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
cytochrome b5	-	Homo sapiens
NADH	-	Homo sapiens

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Release 2023.1 (January 2023)