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Literature summary for 1.14.19.41 extracted from
- Cytochrome P450 subfamily CYP710A genes encode sterol C-22 desaturase in plants (2006), Biochem. Soc. Trans., 34, 1202-1205.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.001 | - |
beta-sitosterol | isoform CYP710A1, pH and temperature not specified in the publication | Arabidopsis thaliana |  |
| 0.0037 | - |
beta-sitosterol | isoform CYP710A2, pH and temperature not specified in the publication | Arabidopsis thaliana | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ergosta-5,7,24(28)-trien-3beta-ol + NADPH + H+ + O2 | Arabidopsis thaliana | - |
ergosta-5,7,22,24(28)-tetraen-3-beta-ol + NADP+ + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | O64697 | - |
- |
| Arabidopsis thaliana | O64698 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 24-epi-campesterol + NADPH + H+ + O2 | substrate for isoform CYP710A2 but not CYP710A1 | Arabidopsis thaliana | brassicasterol + crinosterol + NADP+ + H2O | brassicasterol is the major product | ? | |
| beta-sitosterol + NADPH + H+ + O2 | high affinity substrate | Arabidopsis thaliana | stigmasterol + NADP+ + H2O | - |
? | |
| ergosta-5,7,24(28)-trien-3beta-ol + NADPH + H+ + O2 | - |
Arabidopsis thaliana | ergosta-5,7,22,24(28)-tetraen-3-beta-ol + NADP+ + H2O | - |
? | |
| additional information | 24-epi-campesterol is no substrate for isoform CYP710A1 | Arabidopsis thaliana | ? | brassicasterol is the major product | ? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CYP710A1 | isoform | Arabidopsis thaliana |
| CYP710A2 | isoform | Arabidopsis thaliana |
| sterol C-22 desaturase | - |
Arabidopsis thaliana |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.009 | - |
beta-sitosterol | isoform CYP710A1, pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 0.17 | - |
beta-sitosterol | isoform CYP710A2, pH and temperature not specified in the publication | Arabidopsis thaliana | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Arabidopsis thaliana | |
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Release 2023.1 (January 2023)
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