Any feedback?
Literature summary for 1.14.19.6 extracted from
- New insight into Phaeodactylum tricornutum fatty acid metabolism. Cloning and functional characterization of plastidial and microsomal DELTA12-fatty acid desaturases (2003), Plant Physiol., 131, 1648-1660.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| heterologous expression in yeast Saccharomyces cerevisiae and Synechococcus | Phaeodactylum tricornutum |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | PtFAD2 | Phaeodactylum tricornutum | - |
- |
| plastid | PtFAD6 | Phaeodactylum tricornutum | 9536 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cis-9-octadecenoic acid + reduced acceptor + O2 | Phaeodactylum tricornutum | PtFAD2 is involved in the biosynthesis of eicosapentaenoic acid | cis,cis-9,12-octadecadienoic acid + acceptor + 2 H2O | - |
? |  |
| additional information | Phaeodactylum tricornutum | PtFAD6 is involved in the biosynthesis of hexadecantrienic acid | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Phaeodactylum tricornutum | - |
PtFAD2 | - |
| Phaeodactylum tricornutum | - |
PtFAD6 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cis-7-hexadecenoic acid + reduced acceptor + O2 | 5.2% desaturation | Phaeodactylum tricornutum | cis,cis-7,10-hexadecadienoic acid + acceptor + H2O | - |
? | |
| cis-9-heptadecenoic acid + reduced acceptor + O2 | 22.3% desaturation | Phaeodactylum tricornutum | cis,cis-9,12-heptadecadienoic acid + acceptor + H2O | - |
? | |
| cis-9-hexadecenoic acid + reduced acceptor + O2 | 14.7% desaturation | Phaeodactylum tricornutum | cis,cis-9,12-hexadecadienoic acid + acceptor + H2O | - |
? | |
| cis-9-hexadecenoic acid + reduced acceptor + O2 | 70.3% desaturation | Phaeodactylum tricornutum | cis,cis-9,12-hexadecadienoic acid + acceptor + H2O | - |
? | |
| cis-9-icosenoic acid + reduced acceptor + O2 | 4.1% desaturation | Phaeodactylum tricornutum | cis,cis-11,14-icosadienoic acid + acceptor + H2O | - |
? | |
| cis-9-octadecenoic acid + reduced acceptor + O2 | PtFAD2 is involved in the biosynthesis of eicosapentaenoic acid | Phaeodactylum tricornutum | cis,cis-9,12-octadecadienoic acid + acceptor + 2 H2O | - |
? | |
| cis-9-octadecenoic acid + reduced acceptor + O2 | 20.6% desaturation | Phaeodactylum tricornutum | cis,cis-9,12-octadecadienoic acid + acceptor + 2 H2O | - |
? | |
| cis-9-octadecenoic acid + reduced acceptor + O2 | cis-9-octadecenoic acid is the most efficient substrate for PtFAD2, 50.3% desaturation | Phaeodactylum tricornutum | cis,cis-9,12-octadecadienoic acid + acceptor + 2 H2O | - |
? | |
| additional information | PtFAD6 is involved in the biosynthesis of hexadecantrienic acid | Phaeodactylum tricornutum | ? | - |
? | |
| additional information | no activity with cis-13-docosenoic acid | Phaeodactylum tricornutum | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DELTA12(omega6)-desaturase | - |
Phaeodactylum tricornutum |
| DELTA12-fatty acyl-CoA desaturase | - |
Phaeodactylum tricornutum |
| oleoyl coenzyme A desaturase | - |
Phaeodactylum tricornutum |
| oleoyl-CoA DELTA12 desaturase | - |
Phaeodactylum tricornutum |
| PtFAD2 | - |
Phaeodactylum tricornutum |
| PtFAD6 | - |
Phaeodactylum tricornutum |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
