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Literature summary for 1.14.99.1 extracted from
- On the organization and mechanism of prostaglandin synthetase (1973), J. Biol. Chem., 248, 5673-5678.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Ovis aries | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| arachidonate + reduced acceptor + 2 O2 = prostaglandin H2 + acceptor + H2O | mechanism, enzyme acts both as dioxygenase and as peroxidase | Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seminal vesicle | - |
Ovis aries | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonate + electron donor + O2 | - |
Ovis aries | prostaglandin H2 + oxidized electron donor + H2O | - |
? |  |
| additional information | also catalyzed: transformation of arachidonic acid into prostaglandin E2, prostaglandin F2 alpha and 12-hydroxy-5,8,10-heptadecatrienoic acid | Ovis aries | ? | - |
? | |
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Release 2023.1 (January 2023)
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