Cloned (Comment) | Organism |
---|---|
quantitative real-time RT-PCR enzyme expression analysis | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NS-398 | inhibits PTGS2 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P35354 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bronchial epithelium | - |
Homo sapiens | - |
additional information | quantitative real-time RT-PCR enzyme expression analysis, overview | Homo sapiens | - |
NCI-H292 cell | - |
Homo sapiens | - |
non-small cell lung cancer cell | increased expression of PTGS2 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
Cox2 | - |
Homo sapiens |
cyclooxygenase | - |
Homo sapiens |
prostaglandin G/H synthase | - |
Homo sapiens |
prostaglandin-endoperoxide synthase 2 | - |
Homo sapiens |
PTGS2 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | when NCI-H292 cells are transfected with E2F1 siRNA, PTGS2 expression is attenuated | down |
General Information | Comment | Organism |
---|---|---|
physiological function | PTGS2 plays a pivotal role in inflammation, tissue damage, and tumorigenesis. Differential regulation of PCSKs by PTGS2 with a pivotal role for E2F1, implication of PTGS2-derived PGE2 as a determining factor in the regulation of PCSK activity | Homo sapiens |