Activating Compound | Comment | Organism | Structure |
---|---|---|---|
glutamate-containing substrates | bound to the vitamin K-dependent carboxylase converts its vitamin K epoxidase function from an inactive to an active state | Bos taurus | |
propeptide | bound to the vitamin K-dependent carboxylase converts its vitamin K epoxidase function from an inactive to an active state | Bos taurus |
Cloned (Comment) | Organism |
---|---|
expressed in chinese hamster ovary cells CHO-Dukx-B11 | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | microsomal recombinant protein preparation from chinese hamster ovary cells | Bos taurus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
94000 | - |
x * 94000, SDS-PAGE, wild type enzyme | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phylloquinone + electron donor + O2 | Bos taurus | - |
2,3-epoxyphylloquinone + oxidized electron + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
phylloquinone + reduced acceptor + O2 = 2,3-epoxyphylloquinone + acceptor + H2O | propeptide and glutamate-containing substrates bound to the vitamin K-dependent carboxylase convert its vitamin K epoxidase function from an inactive to an active state | Bos taurus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Bos taurus |
Storage Stability | Organism |
---|---|
-80°C, 20% glycerol | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phylloquinone + electron donor + O2 | - |
Bos taurus | 2,3-epoxyphylloquinone + oxidized electron donor + H2O | - |
? | |
phylloquinone + electron donor + O2 | - |
Bos taurus | 2,3-epoxyphylloquinone + oxidized electron + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 94000, SDS-PAGE, wild type enzyme | Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
enzyme assay | Bos taurus |