Literature summary for 1.14.99.38 extracted from

Chen, J.J.; Lukyanenko, Y.; Hutson, J.C.
25-hydroxycholesterol is produced by testicular macrophages during the early postnatal period and influences differentiation of Leydig cells in vitro (2002), Biol. Reprod., 66, 1336-1341.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
cholesterol + AH2 + O2	Rattus norvegicus	testicular macrophagers play an important role in the differentiation of Leydig cells through the secretion of 25-hydroxycholesterol	25-hydroxycholesterol + A + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
macrophage	testicular, 10-day-old animals have the highest steady-state levels of message	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cholesterol + AH2 + O2	testicular macrophagers play an important role in the differentiation of Leydig cells through the secretion of 25-hydroxycholesterol	Rattus norvegicus	25-hydroxycholesterol + A + H2O	-	?

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Release 2023.1 (January 2023)