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Literature summary for 1.14.99.38 extracted from

  • Diczfalusy, U.; Olofsson, K.; Carlsson, A.; Gong, M.; Golenbock, D.; Rooyackers, O.; Fläring, U.; Björkbacka, H.
    Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide (2009), J. Lipid Res., 50, 2258-2264.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
lipopolysaccharide
-
Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesterol + AH2 + O2 Mus musculus
-
25-hydroxycholesterol + A + H2O
-
?
cholesterol + AH2 + O2 Homo sapiens
-
25-hydroxycholesterol + A + H2O
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage
-
Mus musculus
-
RAW-264.7 cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesterol + AH2 + O2
-
Mus musculus 25-hydroxycholesterol + A + H2O
-
?
cholesterol + AH2 + O2
-
Homo sapiens 25-hydroxycholesterol + A + H2O
-
?

Synonyms

Synonyms Comment Organism
cholesterol 25-hydroxylase
-
Mus musculus
cholesterol 25-hydroxylase
-
Homo sapiens