KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | enzyme redox potentials, and stopped-flow kinetics of the reduction of superoxide reductase-Zn(II)-Fe(III) and superoxide reductase-Fe(III)-Fe(III), overview. Smaller reaction rate constants are observed for the superoxide reductase-Fe(III)-Fe(III) and oxidized superoxide reductase-Zn(II)-Fe(III) forms, in both cases centre II has to be reduced prior to the reaction with superoxide radical, leading to a slower initial reaction rate | Desulfovibrio vulgaris |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | Zn/Fe-superoxide reductase | Desulfovibrio vulgaris | |
additional information | metal content and protein quantification, overview | Desulfovibrio vulgaris | |
Zn2+ | Zn/Fe-superoxide reductase | Desulfovibrio vulgaris |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
reduced desulforedoxin + superoxide + 2 H+ | Desulfovibrio vulgaris | - |
desulforedoxin + H2O2 | - |
? | |
reduced desulforedoxin + superoxide + 2 H+ | Desulfovibrio vulgaris Hildenborough | - |
desulforedoxin + H2O2 | - |
? | |
reduced rubredoxin + superoxide + 2 H+ | Desulfovibrio vulgaris | - |
rubredoxin + H2O2 | - |
? | |
reduced rubredoxin + superoxide + 2 H+ | Desulfovibrio vulgaris Hildenborough | - |
rubredoxin + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Desulfovibrio vulgaris | - |
- |
- |
Desulfovibrio vulgaris Hildenborough | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
reduced desulforedoxin + superoxide + 2 H+ | - |
Desulfovibrio vulgaris | desulforedoxin + H2O2 | - |
? | |
reduced desulforedoxin + superoxide + 2 H+ | - |
Desulfovibrio vulgaris Hildenborough | desulforedoxin + H2O2 | - |
? | |
reduced rubredoxin + superoxide + 2 H+ | - |
Desulfovibrio vulgaris | rubredoxin + H2O2 | - |
? | |
reduced rubredoxin + superoxide + 2 H+ | - |
Desulfovibrio vulgaris Hildenborough | rubredoxin + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
class I SOR | - |
Desulfovibrio vulgaris |
class I superoxide reductase | - |
Desulfovibrio vulgaris |
SOR | - |
Desulfovibrio vulgaris |
Zn/Fe-SOR | - |
Desulfovibrio vulgaris |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
desulforedoxin | from Desufovibrio gigas, recombinantly expressed | Desulfovibrio vulgaris | |
rubredoxin | endogenous rubredoxin, recombinantly expressed | Desulfovibrio vulgaris |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme belongs to the class I superoxide reductase family | Desulfovibrio vulgaris |
additional information | direct electron transfer measurements, in the presence of superoxide anion, overview | Desulfovibrio vulgaris |