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Literature summary for 1.15.1.2 extracted from

  • Folgosa, F.; Cordas, C.M.; Santos, J.A.; Pereira, A.S.; Moura, J.J.; Tavares, P.; Moura, I.
    New spectroscopic and electrochemical insights on a class I superoxide reductase: evidence for an intramolecular electron-transfer pathway (2011), Biochem. J., 438, 485-494.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information enzyme redox potentials, and stopped-flow kinetics of the reduction of superoxide reductase-Zn(II)-Fe(III) and superoxide reductase-Fe(III)-Fe(III), overview. Smaller reaction rate constants are observed for the superoxide reductase-Fe(III)-Fe(III) and oxidized superoxide reductase-Zn(II)-Fe(III) forms, in both cases centre II has to be reduced prior to the reaction with superoxide radical, leading to a slower initial reaction rate Desulfovibrio vulgaris

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ Zn/Fe-superoxide reductase Desulfovibrio vulgaris
additional information metal content and protein quantification, overview Desulfovibrio vulgaris
Zn2+ Zn/Fe-superoxide reductase Desulfovibrio vulgaris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
reduced desulforedoxin + superoxide + 2 H+ Desulfovibrio vulgaris
-
desulforedoxin + H2O2
-
?
reduced desulforedoxin + superoxide + 2 H+ Desulfovibrio vulgaris Hildenborough
-
desulforedoxin + H2O2
-
?
reduced rubredoxin + superoxide + 2 H+ Desulfovibrio vulgaris
-
rubredoxin + H2O2
-
?
reduced rubredoxin + superoxide + 2 H+ Desulfovibrio vulgaris Hildenborough
-
rubredoxin + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Desulfovibrio vulgaris
-
-
-
Desulfovibrio vulgaris Hildenborough
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
reduced desulforedoxin + superoxide + 2 H+
-
Desulfovibrio vulgaris desulforedoxin + H2O2
-
?
reduced desulforedoxin + superoxide + 2 H+
-
Desulfovibrio vulgaris Hildenborough desulforedoxin + H2O2
-
?
reduced rubredoxin + superoxide + 2 H+
-
Desulfovibrio vulgaris rubredoxin + H2O2
-
?
reduced rubredoxin + superoxide + 2 H+
-
Desulfovibrio vulgaris Hildenborough rubredoxin + H2O2
-
?

Synonyms

Synonyms Comment Organism
class I SOR
-
Desulfovibrio vulgaris
class I superoxide reductase
-
Desulfovibrio vulgaris
SOR
-
Desulfovibrio vulgaris
Zn/Fe-SOR
-
Desulfovibrio vulgaris

Cofactor

Cofactor Comment Organism Structure
desulforedoxin from Desufovibrio gigas, recombinantly expressed Desulfovibrio vulgaris
rubredoxin endogenous rubredoxin, recombinantly expressed Desulfovibrio vulgaris

General Information

General Information Comment Organism
evolution the enzyme belongs to the class I superoxide reductase family Desulfovibrio vulgaris
additional information direct electron transfer measurements, in the presence of superoxide anion, overview Desulfovibrio vulgaris