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Literature summary for 1.16.3.1 extracted from

  • Gray, L.W.; Kidane, T.Z.; Nguyen, A.; Akagi, S.; Petrasek, K.; Chu, Y.L.; Cabrera, A.; Kantardjieff, K.; Mason, A.Z.; Linder, M.C.
    Copper proteins and ferroxidases in human plasma and that of wild-type and ceruloplasmin knockout mice (2009), Biochem. J., 419, 237-245.
    View publication on PubMed
Search for more literature for 1.16.3.1

Inhibitors

Inhibitors Comment Organism Structure
Sodium azide 1-2.5 mM sodium azide reduces ferroxidase activity markedly Homo sapiens
Sodium azide 1-2.5 mM sodium azide reduces ferroxidase activity markedly Mus musculus
Sodium azide 1-2.5 mM sodium azide reduces ferroxidase activity markedly Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens P00450
-
-
Mus musculus Q61147 wild-type and ceruloplasmin knockout mice
-
Rattus norvegicus
-
-
-
Rattus norvegicus Sprague-Dawley
-
-
-

Purification (Commentary)

Purification (Comment) Organism
blood plasma ceruloplasmin was purified by DEAE-Sepharose chromatography Rattus norvegicus
blood plasma ceruloplasmin was purified by DEAE-Sepharose chromatography Homo sapiens
blood plasma ceruloplasmin was purified by DEAE-Sepharose chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Rattus norvegicus
-
blood plasma
-
 Homo sapiens
-
blood plasma
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.25
-
 in an Erel assay measuring loss of Fe2+ Mus musculus
0.3
-
 in a transferrin assay measuring transformation of apotransferrin to holotransferrin Mus musculus
0.58
-
 in an Erel assay measuring loss of Fe2+ Homo sapiens
1.25
-
 in a transferrin assay measuring transformation of apotransferrin to holotransferrin Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
apotransferrin + Fe2+
-
 Rattus norvegicus holotransferrin + ?
-
 ?
apotransferrin + Fe2+
-
 Homo sapiens holotransferrin + ?
-
 ?
apotransferrin + Fe2+
-
 Mus musculus holotransferrin + ?
-
 ?
apotransferrin + Fe2+
-
 Rattus norvegicus Sprague-Dawley holotransferrin + ?
-
 ?
Fe2+ + H+ + O2
-
 Rattus norvegicus Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2
-
 Homo sapiens Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2
-
 Mus musculus Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2
-
 Rattus norvegicus Sprague-Dawley Fe3+ + H2O
-
 ?

Synonyms

Synonyms Comment Organism
ferroxidase
-
 Rattus norvegicus
ferroxidase
-
 Homo sapiens
ferroxidase
-
 Mus musculus
mouse ceruloplasmin ceruloplasmin with ferroxidase activity detected by native PAGE Mus musculus