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Literature summary for 1.17.1.4 extracted from

  • Wajner, M.; Harkness, R.A.
    Distribution of xanthine dehydrogenase and oxidase activities in human and rabbit tissues (1988), Biochem. Soc. Trans., 16, 358-359.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
xanthine + NAD+ + H2O Homo sapiens
-
urate + NADH
-
r
xanthine + NAD+ + H2O Oryctolagus cuniculus
-
urate + NADH
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Oryctolagus cuniculus
-
rabbit
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
Homo sapiens
-
cerebellum
-
Oryctolagus cuniculus
-
cerebellum high rate of dehydrogenase activity Homo sapiens
-
cerebral cortex
-
Oryctolagus cuniculus
-
cerebral cortex high rate of dehydrogenase activity Homo sapiens
-
heart
-
Oryctolagus cuniculus
-
heart high rate of dehydrogenase activity Homo sapiens
-
kidney
-
Homo sapiens
-
liver high oxidase and reductase activities at nearly the same rates Homo sapiens
-
liver high oxidase and reductase activities at nearly the same rates Oryctolagus cuniculus
-
placenta very low oxidase and dehydrogenase activities Homo sapiens
-
pons
-
Oryctolagus cuniculus
-
pons high rate of dehydrogenase activity Homo sapiens
-
skeletal muscle low oxidase activity Homo sapiens
-
spleen
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xanthine + NAD+ + H2O
-
Homo sapiens urate + NADH
-
r
xanthine + NAD+ + H2O
-
Oryctolagus cuniculus urate + NADH
-
r

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens
NAD+
-
Oryctolagus cuniculus
NADH
-
Homo sapiens
NADH
-
Oryctolagus cuniculus