Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NO | dose-dependent inhibition of xanthine dehydrogenase and oxidase activity, reaction with an essential sulfur in the molybdenum center, that damages the molybdopterin | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron-sulfur-center | 2 Fe2-S2-clusters | Bos taurus | |
molybdenum-center | - |
Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + NAD+ + H2O | Bos taurus | NAD+-dependent dehydrogenase type D | urate + NADH | - |
? | |
xanthine + O2 + H2O | Bos taurus | - |
urate + O2- + 2 H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
milk | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + NAD+ + H2O | NAD+-dependent dehydrogenase type D | Bos taurus | urate + NADH | - |
? | |
xanthine + O2 + H2O | - |
Bos taurus | urate + O2- + 2 H+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Bos taurus | |
NAD+ | - |
Bos taurus |