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Literature summary for 1.17.3.2 extracted from

  • Huang, X.F.; Li, H.Q.; Shi, L.; Xue, J.Y.; Ruan, B.F.; Zhu, H.L.
    Synthesis of resveratrol analogues, and evaluation of their cytotoxic and xanthine oxidase inhibitory activities (2008), Chem. Biodivers., 5, 636-642.
    View publication on PubMed
Search for more literature for 1.17.3.2

Inhibitors

Inhibitors Comment Organism Structure
2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]benzaldehyde
-
 Homo sapiens
2-hydroxy-4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]benzaldehyde a resveratrol derivative Homo sapiens
2-hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-4-methoxybenzaldehyde a resveratrol derivative Homo sapiens
allopurinol
-
 Homo sapiens
additional information inhibitory potencies and cytotoxicity of resveratrol derivatives, no inhibition of xanthine oxidase by 4,6-dihydroxy-2-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-dicarbaldehyde, 4-(3-bromopropoxy)-2-((E)-2-[4-(3-bromopropoxy)phenyl]ethenyl)-6-hydroxybenzaldehyde, 2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]benzaldehyde, ethyl (4-formyl-3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy)acetate, ethyl (4-((E)-2-[5-(2-ethoxy-2-oxoethoxy)-2-formyl-3-hydroxyphenyl]ethenyl)phenoxy)acetate, ethyl (4-((E)-2-[3,5-bis(2-ethoxy-2-oxoethoxy)-2-formylphenyl]ethenyl)phenoxy)acetate, and 4-(3-bromopropoxy)-2-hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]benzaldehyde, overview Homo sapiens
resveratrol i.e. 5[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol, found in grapes as well as in other plants, is a natural phytoalexin, which is biosynthesized in response to pathogenic attack or other stress conditions Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
carcinoma cell
-
 Homo sapiens
-
commercial preparation
-
 Homo sapiens
-
KB cell a nasopharyngeal epidermoid tumor cell line Homo sapiens
-

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
 assay at Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0025
-
 pH 7.8, 25°C Homo sapiens 2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]benzaldehyde
0.0134
-
 pH 7.8, 25°C Homo sapiens allopurinol
0.0139
-
 pH 7.8, 25°C Homo sapiens resveratrol
0.0169
-
 pH 7.8, 25°C Homo sapiens 2-hydroxy-4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]benzaldehyde
0.0266
-
 pH 7.8, 25°C Homo sapiens 2-hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-4-methoxybenzaldehyde