Literature summary for 1.17.4.1 extracted from

Stubbe, J.; Ator, M.; Krenitsky, T.
Mechanism of ribonucleoside diphosphate reductase from Escherichia coli. Evidence for 3-C-H bond cleavage (1983), J. Biol. Chem., 258, 1625-1630.

Search for more literature for 1.17.4.1

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin	NDP reduction requires cleavage of the 3'-C-H bond of the substrate, hypothesis of enzyme mechanism	Escherichia coli	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ribonucleoside diphosphate + reduced thioredoxin	-	Escherichia coli	2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O	-	ir

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)