Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2'-methyladenosine 5'-diphosphate | probably mechanism based inhibition, competitive inhibition vs. ADP and GDP | Corynebacterium nephridii | |
2'-methyluridine 5'-diphosphate | probably mechanism based inhibition, competitive inhibition vs. UDP and CDP | Corynebacterium nephridii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium nephridii | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2'-methyladenosine 5'-diphosphate + reduced dithiothreitol | - |
Corynebacterium nephridii | adenine + 2'-deoxy-2'-methyladenosine + H2O | 5% reduction to 2'-deoxy-2'-methyladenosine, adenine is the major product besides other unidentified products | ? | |
2'-methyluridine 5'-diphosphate + reduced dithiothreitol | - |
Corynebacterium nephridii | uracil + H2O + ? | uracil is the major product, unidentified minor product may be 2'-deoxy-2'-methyluridine | ? | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Corynebacterium nephridii | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0037 | - |
2'-methyladenosine 5'-diphosphate | vs. ADP | Corynebacterium nephridii | |
0.0079 | - |
2'-methyladenosine 5'-diphosphate | vs. GDP | Corynebacterium nephridii | |
0.084 | - |
2'-methyluridine 5'-diphosphate | vs. UDP | Corynebacterium nephridii | |
0.115 | - |
2'-methyluridine 5'-diphosphate | vs. CDP | Corynebacterium nephridii |