Protein Variants | Comment | Organism |
---|---|---|
N238A | the monomeric R1 protein is able to dimerize when bound by both substrate and effector and is able to reduce ribonucleotides with a comparatively high capacity | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | each catalytic turnover by aerobic ribonucleotide reductase requires the assembly of the two proteins, R1 (alpha2) and R2 (beta2), to produce deoxyribonucleotides for DNA synthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CDP + reduced thioredoxin | - |
Escherichia coli | 2'-dCDP + thioredoxin disulfide + H2O | - |
? | |
CTP + reduced thioredoxin | - |
Escherichia coli | 2'-dCTP + thioredoxin disulfide + H2O | - |
? | |
additional information | each catalytic turnover by aerobic ribonucleotide reductase requires the assembly of the two proteins, R1 (alpha2) and R2 (beta2), to produce deoxyribonucleotides for DNA synthesis | Escherichia coli | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | each catalytic turnover by aerobic ribonucleotide reductase requires the assembly of the two proteins, R1 (alpha2) and R2 (beta2), to produce deoxyribonucleotides for DNA synthesis | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
ribonucleotide reductase | - |
Escherichia coli |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | turnover number of wild-type and mutant proteins of R1 protein | Escherichia coli |