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Literature summary for 1.17.4.1 extracted from

  • Sanchez-Romero, M.A.; Molina, F.; Jimenez-Sanchez, A.
    Organization of ribonucleoside-diphosphate reductase during multifork chromosome replication in Escherichia coli (2011), Microbiology, 157, 2220-2225.
    View publication on PubMed
Search for more literature for 1.17.4.1

Cloned(Commentary)

Cloned (Comment) Organism
genes nrdA and nrdB, expression of FLAG-tagged subunits R1 and R2 in Escherichia coli strains CMT931 and CMT933 Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information RNR is located in discrete foci in a number that increases with the overlapping of replication cycles in Escherichia coli, higher amount of RNR per focus at faster growth rates Escherichia coli
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Organism

Organism UniProt Comment Textmining
Escherichia coli
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 genes nrdA and nrdB encoding subunits R1 and R2, respectively
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Escherichia coli K-12 CM735
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 genes nrdA and nrdB encoding subunits R1 and R2, respectively
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Source Tissue

Source Tissue Comment Organism Textmining
additional information class I RNR predominates in aerobically grown cells Escherichia coli
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Subunits

Subunits Comment Organism
tetramer class I RNR is a tetramer formed by two homodimers, subunit R1 encoded by the nrdA gene and subunit R2 encoded by the nrdB gene Escherichia coli

Synonyms

Synonyms Comment Organism
class I RNR
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 Escherichia coli
NrdA
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 Escherichia coli
NrdB
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 Escherichia coli
RNR
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 Escherichia coli

General Information

General Information Comment Organism
physiological function ribonucleoside diphosphate reductase is an essential enzyme for the biosynthesis of the four dNTP in all living cells Escherichia coli