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Literature summary for 1.17.4.2 extracted from

  • Bakley, R.L.
    Cobamides and ribonucleotide reduction. I. Cobamide stimulation of ribonucleotide reduction in extracts of Lactobacillus leichmannii (1965), J. Biol. Chem., 240, 2173-2180.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
2',5'-dideoxyadenosylcobalamin anilide
-
Lactobacillus leichmannii
2-mercaptoethanol
-
Lactobacillus leichmannii
5'-deoxyadenosylcobalamin
-
Lactobacillus leichmannii
5'-deoxyadenosylcobalamin anilide
-
Lactobacillus leichmannii
5'-deoxyuridylcobalamin
-
Lactobacillus leichmannii
cobinamide
-
Lactobacillus leichmannii
cyanocobalamin
-
Lactobacillus leichmannii
cyanocobalamin anilide
-
Lactobacillus leichmannii
cyanocobalamin dibasic acid
-
Lactobacillus leichmannii
cyanocobalamin ethylamide
-
Lactobacillus leichmannii
cyanocobalamin monobasic acid
-
Lactobacillus leichmannii
ethyl cobalamin
-
Lactobacillus leichmannii
hydroxocobalamin
-
Lactobacillus leichmannii
hydroxocobalamin methylamide
-
Lactobacillus leichmannii
methyl cobalamin
-
Lactobacillus leichmannii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ribonucleoside triphosphate + reduced thioredoxin + H2O Lactobacillus leichmannii
-
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
r

Organism

Organism UniProt Comment Textmining
Lactobacillus leichmannii
-
mutant of strain ATCC 4797, produced during many years of transfers on litmus milk
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + reduced thioredoxin
-
Lactobacillus leichmannii dCTP + oxidized thioredoxin + H2O
-
?
ribonucleoside triphosphate + reduced thioredoxin
-
Lactobacillus leichmannii 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
r
ribonucleoside triphosphate + reduced thioredoxin + H2O
-
Lactobacillus leichmannii 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
r