Literature summary for 1.2.1.24 extracted from

Kumar, S.; Punekar, N.S.
Inhibition of succinic semialdehyde dehydrogenase by N-formylglycine (1998), J. Enzyme Inhib., 13, 369-376.

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Inhibitors

Inhibitors	Comment	Organism	Structure
N-formylglycine	4 mM, 40% inhibition, reversible, competitive with respect to succinate semialdehyde, uncompetitive with respect to NAD+	Aspergillus niger

Organism

Organism	UniProt	Comment	Textmining
Aspergillus niger	-	-	-
Solanum tuberosum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
succinate semialdehyde + NAD+ + H2O	-	Aspergillus niger	succinate + NADH	-	?
succinate semialdehyde + NAD+ + H2O	-	Solanum tuberosum	succinate + NADH	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Aspergillus niger
NAD+	-	Solanum tuberosum

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Release 2023.1 (January 2023)