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Literature summary for 1.2.1.3 extracted from
- Kinetics of p-nitrophenyl pivalate hydrolysis catalysed by cytoplasmic aldehyde dehydrogenase (1989), Biochem. J., 257, 573-578.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Chloral hydrate | competitive inhibition of hydrolysis of p-nitrophenyl acetate, mixed inhibition with p-nitrophenyl pivalate | Ovis aries |  |
| p-nitrophenyl pivalate | inhibits dehydrogenase activity with propanal and D-glyceraldehyde | Ovis aries | |
| propanal | competitive inhibition of hydrolysis of p-nitrophenyl acetate, mixed inhibition with p-nitrophenyl pivalate | Ovis aries | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Ovis aries | 5737 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Ovis aries | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glyceraldehyde + NAD+ + H2O | - |
Ovis aries | glycerate + NADH | - |
? | |
| additional information | the enzyme also catalyzes esterase reaction with p-nitrophenylacetate + H2O | Ovis aries | ? | - |
? | |
| additional information | enzyme also catalyzes esterase reaction with p-nitrophenyl pivalate + H2O | Ovis aries | ? | - |
? | |
| propanal + NAD+ + H2O | - |
Ovis aries | propionate + NADH | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Ovis aries | |
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