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Literature summary for 1.2.1.3 extracted from
- Kinetic properties of aldehyde dehydrogenase from sheep liver mitochondria (1978), Biochem. J., 175, 899-908.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | stimulates hydrolysis of p-nitrophenyl esters | Ovis aries |  |
| NADH | stimulates hydrolysis of p-nitrophenyl esters | Ovis aries | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Disulfiram | - |
Ovis aries | |
| iodoacetamide | - |
Ovis aries | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.036 | - |
NAD+ | reaction with acetaldehyde | Ovis aries | |
| 0.038 | - |
NAD+ | reaction with butanal | Ovis aries | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Ovis aries | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Ovis aries | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetaldehyde + NAD+ + H2O | - |
Ovis aries | acetate + NADH + H+ | - |
? | |
| butanal + NAD+ + H2O | - |
Ovis aries | butyrate + NADH + H+ | - |
? | |
| additional information | - |
Ovis aries | ? | - |
? | |
| propanal + NAD+ + H2O | - |
Ovis aries | propionate + NADH | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Ovis aries | |
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