Literature summary for 1.2.1.3 extracted from

Daiber, A.; Wenzel, P.; Oelze, M.; Schuhmacher, S.; Jansen, T.; Muenzel, T.
Mitochondrial aldehyde dehydrogenase (ALDH-2)--maker of and marker for nitrate tolerance in response to nitroglycerin treatment (2009), Chem. Biol. Interact., 178, 40-47.

Search for more literature for 1.2.1.3

Application

Application	Comment	Organism
medicine	white blood cell ALDH activity is a reliable marker for organic nitrate tachyphylaxis and may be a useful marker for clinical tolerance as well	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
benomyl	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Homo sapiens	5739	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
an aldehyde + NAD+ + H2O	Homo sapiens	-	an acid + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
artery	-	Homo sapiens	-
lymphocyte	-	Homo sapiens	-
monocyte	-	Homo sapiens	-
neutrophil	-	Homo sapiens	-
vein	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-hydroxy-3-nitrobenzaldehyde + NAD+ + H2O	-	Homo sapiens	2-hydroxy-3-nitrobenzoic acid + NADH + H+	-	?
an aldehyde + NAD+ + H2O	-	Homo sapiens	an acid + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
aldehyde dehydrogenase	-	Homo sapiens
ALDH-2	-	Homo sapiens
mitochondrial aldehyde dehydrogenase	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Homo sapiens

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Release 2023.1 (January 2023)