Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cholecalciferol | 0.2 mM, activation to 136% of the control | Xenopus laevis |
Cloned (Comment) | Organism |
---|---|
expression of xCTBP/xALDH1 in Escherichia coli | Xenopus laevis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,3',5-Triiodothyroacetic acid | 0.001 mM, 60% inhibition | Xenopus laevis | |
D-3,3',5-triiodothyronine | 0.001 mM, 65% inhibition | Xenopus laevis | |
Disulfiram | 0.2 mM, 58% inhibition | Xenopus laevis | |
L-thyroxine | 0.001 mM, 64% inhibition | Xenopus laevis | |
NADH | 0.2 mM, 62% inhibition | Xenopus laevis | |
NADPH | 0.2 mM, 79% inhibition | Xenopus laevis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Xenopus laevis | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Xenopus laevis | the enzyme xCTBP/xALDH1 binds T3 within living cells | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Xenopus laevis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Xenopus laevis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme xCTBP/xALDH1 binds T3 within living cells | Xenopus laevis | ? | - |
? | |
retinal + NAD+ + H2O | - |
Xenopus laevis | retinoic acid + NADH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ALDH1 | - |
Xenopus laevis |
thyroid-hormone-binding protein | - |
Xenopus laevis |
xCTBP | - |
Xenopus laevis |
xCTBP/xALDH1 | - |
Xenopus laevis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Xenopus laevis |