Literature summary for 1.2.1.36 extracted from

Kern, J.; Schrage, K.; Koopmans, G.C.; Joosten, E.A.; McCaffery, P.; Mey, J.
Characterization of retinaldehyde dehydrogenase-2 induction in NG2-positive glia after spinal cord contusion injury (2007), Int. J. Dev. Neurosci., 25, 7-16.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	spinal cord injury results in a significant rise in RALDH2 protein expression that is accounted for by an increase of this enzyme in meninges, blood vessels and a subpopulation of NG2-positive cells	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
55000	-	Western blot analysis	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	male Lewis rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	NG2-positive cell	Rattus norvegicus	-
spinal cord	in the uninjured spinal cord low levels of RALDH2 are present in oligodendrocytes as well as in the meninges and in blood vessels	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
retinal + NAD+ + H2O	-	Rattus norvegicus	retinoate + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
RALDH2	-	Rattus norvegicus
retinaldehyde dehydrogenase-2	-	Rattus norvegicus

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Release 2023.1 (January 2023)