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Literature summary for 1.2.1.44 extracted from

  • Tamasloukht, B.; Wong Quai Lam, M.S.; Martinez, Y.; Tozo, K.; Barbier, O.; Jourda, C.; Jauneau, A.; Borderies, G.; Balzergue, S.; Renou, J.P.; Huguet, S.; Martinant, J.P.; Tatout, C.; Lapierre, C.; Barriere, Y.; Goffner, D.; Pichon, M.
    Characterization of a cinnamoyl-CoA reductase 1 (CCR1) mutant in maize: effects on lignification, fibre development, and global gene expression (2011), J. Exp. Bot., 62, 3837-3848.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 cells Zea mays

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0028
-
 4-coumaroyl-CoA pH and temperature not specified in the publication Zea mays
0.00658
-
 sinapoyl-CoA pH and temperature not specified in the publication Zea mays
0.00926
-
 feruloyl-CoA pH and temperature not specified in the publication Zea mays

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-coumaroyl-CoA + NADPH + H+ Zea mays
-
 4-coumaraldehyde + CoA + NADP+
-
 ?
feruloyl-CoA + NADPH + H+ Zea mays
-
 coniferaldehyde + CoA + NADP+
-
 ?
sinapoyl-CoA + NADPH + H+ Zea mays
-
 sinapaldehyde + CoA + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Zea mays
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-coumaroyl-CoA + NADPH + H+
-
 Zea mays 4-coumaraldehyde + CoA + NADP+
-
 ?
feruloyl-CoA + NADPH + H+
-
 Zea mays coniferaldehyde + CoA + NADP+
-
 ?
sinapoyl-CoA + NADPH + H+
-
 Zea mays sinapaldehyde + CoA + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
CCR1
-
 Zea mays
cinnamoyl-CoA reductase 1
-
 Zea mays

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Zea mays

General Information

General Information Comment Organism
malfunction in the ccr1 mutant, CCR1 gene expression is reduced to 31% of the residual wild type level leading to a decrease in lignin content and significant changes in lignin structure. 4-hydroxyphenyl units are strongly decreased and the syringyl/guaiacyl ratio is slightly increased. Down-regulation of CCR1 alters schlerenchymatic fibre morphology and cell wall structure. Moderate down-regulation of CCR1 significantly improves cell wall digestibility in maize Zea mays