Protein Variants | Comment | Organism |
---|---|---|
E140D | Km-value for NADP+ is about half that of the native enzyme, Km-value for NAD+ is about 3.1fold that of the native enzyme, Km-value for benzaldehyde is about 1.4fold that of the native enzyme, Km-value for propanal is about 1.9fold that of the native enzyme. The coenzyme preference NADP+/NAD+ is 3.2, compared to 3.4 for the native enzyme | Rattus norvegicus |
E140N | Km-value for NADP+ is about 10% of that of the native enzyme, Km-value for NAD+ is about 3.2fold that of the native enzyme, Km-value for benzaldehyde is about 1.2fold that of the native enzyme, Km-value for propanal is about 2.3fold that of the native enzyme. The coenzyme preference NADP+/NAD+ is 4.2, compared to 3.4 for the native enzyme | Rattus norvegicus |
E140Q | Km-value for NADP+ is about 10% of that of the native enzyme, Km-value for NAD+ is about 7.9fold that of the native enzyme, Km-value for benzaldehyde is about 1.6fold that of the native enzyme, Km-value for propanal is about 1.1fold that of the native enzyme. The coenzyme preference NADP+/NAD+ is 2.8, compared to 3.4 for the native enzyme | Rattus norvegicus |
E140T | Km-value for NADP+ is about 20% of that of the native enzyme, Km-value for NAD+ is about 15.3fold that of the native enzyme, Km-value for benzaldehyde is about 60% of that of the native enzyme, Km-value for propanal is about 1.4fold that of the native enzyme. The coenzyme preference NADP+/NAD+ is 5.8, compared to 3.4 for the native enzyme | Rattus norvegicus |
G192A | Km-value for NADP+ is about half that of the native enzyme, Km-value for NAD+ is about 70% of that of the native enzyme, Km-value for benzaldehyde is about 90% of that of the native enzyme, Km-value for propanal is about 45% of that of the native enzyme | Rattus norvegicus |
K137Q | Km-value for NADP+ is about 2.4fold that of the native enzyme, Km-value for NAD+ is about 16fold that of the native enzyme, Km-value for benzaldehyde is about 1.2fold that of the native enzyme, Km-value for propanal is about 95% of that of the native enzyme. The coenzyme preference NADP+/NAD+ is 1.1, compared to 3.4 for the native enzyme | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzaldehyde + NADP+ | - |
Rattus norvegicus | benzoate + NADPH | - |
? | |
propanal + NAD+ + H2O | - |
Rattus norvegicus | propionate + NADH + H+ | - |
? |