Cloned (Comment) | Organism |
---|---|
heterologous expression of pYES2.1 plasmid harbouring AmFAR1 in Saccharomyces cerevisiae strain INVSc1 | Apis mellifera |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
59200 | - |
calculated from sequence | Apis mellifera |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Apis mellifera | D9MWM7 | honey bee | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
head | predominance, expression level of AmFAR1 in head approximately three times higher than in thorax and abdomen | Apis mellifera | - |
additional information | AmFAR1 ubiquitously expressed in all body segments | Apis mellifera | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
a long-chain fatty acyl-CoA + NADPH + H+ | AmFAR1 converts saturated fatty acids ranging from 16 to 22 carbon chains to their corresponding alcohols with the highest conversion efficiency shown on 18:0, AmFAR1 also shows some activities on ricinoleic acid, 16:1n-7 and 18:1n-9 | Apis mellifera | a long-chain aldehyde + CoA + NADP+ | aldehyde intermediate is immediately reduced to the corresponding alcohol | ? | |
additional information | no activity observed on 18:2n-6 and 18:3n-3 | Apis mellifera | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AmFAR1 | - |
Apis mellifera |
fatty acyl-CoA reductase | - |
Apis mellifera |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
35 | - |
- |
Apis mellifera |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
15 | 40 | - |
Apis mellifera |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 7.5 | - |
Apis mellifera |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | no activity with NADH | Apis mellifera |
General Information | Comment | Organism |
---|---|---|
metabolism | enzyme is involved in the conversion of a wide range of fatty acids to their corresponding alcohols, which are the essential components of pheromones, wax esters or ether lipids | Apis mellifera |