Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cimetidine | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0014 | - |
4-trimethylaminobutyraldehyde | cytoplasmic enzyme | Rattus norvegicus | |
0.004 | - |
4-Aminobutyraldehyde | mitochondrial enzyme | Rattus norvegicus | |
0.014 | - |
acetaldehyde | mitochondrial enzyme | Rattus norvegicus | |
0.024 | - |
4-Aminobutyraldehyde | cytoplasmic enzyme | Rattus norvegicus | |
0.028 | - |
NAD+ | cytoplasmic enzyme | Rattus norvegicus | |
0.034 | - |
NAD+ | mitochondrial enzyme | Rattus norvegicus | |
0.115 | - |
acetaldehyde | cytoplasmic enzyme | Rattus norvegicus | |
0.118 | - |
Betaine aldehyde | mitochondrial enzyme | Rattus norvegicus | |
0.123 | - |
Betaine aldehyde | cytoplasmic enzyme | Rattus norvegicus | |
0.152 | - |
glycolaldehyde | mitochondrial enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | cytoplasmic and mitochondrial enzymes are products of the same gene | Rattus norvegicus | 5737 | - |
mitochondrion | matrix. Cytoplasmic and mitochondrial enzymes are products of the same gene | Rattus norvegicus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
4 * 55000, cytoplasmic enzyme, SDS-PAGE | Rattus norvegicus |
494000 | - |
cytoplasmic enzyme | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | enzyme may be processed in the mitochondria | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-aminobutyraldehyde + NAD+ + H2O | - |
Rattus norvegicus | 4-aminobutyrate + NADH | - |
? | |
4-trimethylaminobutyraldehyde + NAD+ + H2O | - |
Rattus norvegicus | 3-trimethylaminobutyrate + NADH | - |
? | |
acetaldehyde + NAD+ + H2O | - |
Rattus norvegicus | acetate + NADH + H+ | - |
? | |
betaine aldehyde + NAD+ + H2O | - |
Rattus norvegicus | betaine + NADH | - |
? | |
glycolaldehyde + NAD+ + H2O | - |
Rattus norvegicus | glycolate + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 55000, cytoplasmic enzyme, SDS-PAGE | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.033 | - |
cimetidine | - |
Rattus norvegicus |