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Literature summary for 1.2.1.88 extracted from

  • Herzfeld, A.; Mezl, V.A.; Knox, W.E.
    Enzymes metabolizing delta1-pyrroline-5-carboxylate in rat tissues (1977), Biochem. J., 166, 95-103.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.88

Inhibitors

Inhibitors Comment Organism Structure
L-5-oxoproline
-
 Rattus norvegicus
L-hydroxyproline
-
 Rattus norvegicus
N-ethylmaleimide
-
 Rattus norvegicus
p-hydroxymercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.18
-
 1-pyrroline-5-carboxylate
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
additional information distribution in rat tissues Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-pyrroline-5-carboxylate + NAD+ + H2O
-
 Rattus norvegicus L-glutamate + NADH
-
 ir
1-pyrroline-5-carboxylate + NAD+ + H2O
-
 Rattus norvegicus L-glutamate + NADH + H+
-
 r
additional information not: glyceraldehyde, valeraldehyde Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.7 7.7
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NAD+ preferentially Rattus norvegicus