Literature summary for 1.2.1.95 extracted from

Yan, H.; He, P.; Cheng, H.R.; Shen, A.; Jiang, N.
Cloning, sequencing and characterization of the alpha-aminoadipate reductase gene (LYS2) from Saccharomycopsis fibuligera (2007), Yeast, 24, 189-199.

Search for more literature for 1.2.1.95

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	growth on medium containing lysine as the sole nitrogen source	Saccharomycopsis fibuligera

Application

Application	Comment	Organism
additional information	the sequence of the Saccharomycopsis fibuligera alpha-aminoadipate reductase gene Lys2p has the highest identity of 53% with the AAR of Candida albicans SC5314 and an identity of 51% with that of Saccharomyces cerevisiae. Expression of the ORF of SfLYS2 in a lys2- strain of Saccharomyces cerevisiae can functionally complement the lysine mutant of the Saccharomyces cerevisiae strain. Cloning of SfLYS2 may provide a general tool in developing genetics-based studies not only with Saccharomycopsis fibuligera but also with Saccharomyces cerevisiae	Saccharomycopsis fibuligera

Cloned(Commentary)

Cloned (Comment)	Organism
expression of the ORF of the Saccharomycopsis fibuligera alpha-aminoadipate reductase gene (LYS2) in a lys2- strain of Saccharomyces cerevisiae	Saccharomycopsis fibuligera

Inhibitors

Inhibitors	Comment	Organism	Structure
alpha-aminoadipate	inhibitory effect can be reversed by adding methionine	Saccharomycopsis fibuligera

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Saccharomycopsis fibuligera	Q1W284	-	-
Saccharomycopsis fibuligera PD70	Q1W284	-	-

Synonyms

Synonyms	Comment	Organism
AAR	-	Saccharomycopsis fibuligera
alpha-aminoadipate reductase	-	Saccharomycopsis fibuligera

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Release 2023.1 (January 2023)