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Literature summary for 1.2.3.1 extracted from
- Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats (2006), Drug Metab. Dispos., 34, 208-212.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | measurements of NMN and its pyridones usually excreted in the urine can be used to predict the in vivo activity of enzyme | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
marked variations in enzyme activity of different strains | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N1-methylnicotinamide + H2O + O2 | variations in the ratio of the amount of pyridones to the total amount of NMN and pyridones in urine are closely related to the enzyme activity | Rattus norvegicus | N1-methyl-2-pyridone-5-carboxamide + N1-methyl-4-pyridone-3-carboxamide + ? | - |
? |  |
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